The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 493: serine/threonine-protein kinase unc-51 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q23023 (/IPI) Q8MQJ7 (/IPI) Q9VU14 (/IPI)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Ubiquitin-like protein binding GO:0032182
Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein.
2 Q8MQJ7 (/IPI) Q9VU14 (/IPI)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q23023 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q8MQJ7 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q23023 (/ISS)

There are 43 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Autophagy GO:0006914
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
3 Q23023 (/IGI) Q8MQJ7 (/IGI) Q9VU14 (/IGI)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Autophagy GO:0006914
The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 Q8MQJ7 (/IGI) Q9VU14 (/IGI)
Axo-dendritic transport GO:0008088
The directed movement of organelles or molecules along microtubules in neuron projections.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Regulation of autophagy GO:0010506
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
2 Q8MQJ7 (/IGI) Q9VU14 (/IGI)
Regulation of autophagy GO:0010506
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Negative regulation of phosphatidylinositol 3-kinase signaling GO:0014067
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Negative regulation of TOR signaling GO:0032007
Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 Q8MQJ7 (/IDA) Q9VU14 (/IDA)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Larval midgut histolysis GO:0035069
The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Larval midgut cell programmed cell death GO:0035096
The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Nurse cell apoptotic process GO:0045476
Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Positive regulation of glycogen catabolic process GO:0045819
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Positive regulation of nurse cell apoptotic process GO:0045850
Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Synapse organization GO:0050808
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Synaptic growth at neuromuscular junction GO:0051124
The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Glycophagy GO:0061723
The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Regulation of terminal button organization GO:2000331
Any process that modulates the frequency, rate or extent of terminal button organization.
2 Q8MQJ7 (/IMP) Q9VU14 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q23023 (/IDA)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
1 Q23023 (/IMP)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 Q23023 (/IMP)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 Q23023 (/IGI)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
1 Q23023 (/IMP)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 Q23023 (/IGI)
Programmed cell death GO:0012501
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
1 Q23023 (/IGI)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
1 Q23023 (/IMP)
Regulation of axon extension GO:0030516
Any process that modulates the rate, direction or extent of axon extension.
1 Q23023 (/IMP)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
1 Q23023 (/IMP)
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
1 Q23023 (/IGI)
Dauer larval development GO:0040024
The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
1 Q23023 (/IGI)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
1 Q23023 (/IMP)
Nematode male tail tip morphogenesis GO:0045138
The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.
1 Q23023 (/IMP)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
1 Q23023 (/IDA)
Intestinal epithelial structure maintenance GO:0060729
A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.
1 Q8MQJ7 (/IMP)
Lipophagy GO:0061724
The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions.
1 Q8MQJ7 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Atg1/ULK1 kinase complex GO:1990316
A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.
2 Q8MQJ7 (/IDA) Q9VU14 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q23023 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q23023 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q23023 (/IDA)