The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Transferase(Phosphotransferase) domain 1
".
FunFam 1177: eukaryotic translation initiation factor 2-alpha k...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
3 | Q4Q2Y5 (/ISM) Q584D7 (/ISM) Q584D7 (/ISM) |
|
Elongation factor-2 kinase activity GO:0004686
Catalysis of the reaction: ATP +
|
3 | Q4Q2Y5 (/ISA) Q584D7 (/ISA) Q584D7 (/ISA) |
|
Eukaryotic translation initiation factor 2alpha kinase activity GO:0004694
Catalysis of the reaction: ATP +
|
3 | Q4Q2Y5 (/ISO) Q584D7 (/ISO) Q584D7 (/ISO) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
3 | Q4Q2Y5 (/ISM) Q584D7 (/ISM) Q584D7 (/ISM) |
|
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
|
3 | Q4Q2Y5 (/ISO) Q584D7 (/ISO) Q584D7 (/ISO) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
3 | Q4Q2Y5 (/ISM) Q584D7 (/ISM) Q584D7 (/ISM) |
|
Regulation of translational initiation by eIF2 alpha phosphorylation GO:0010998
Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
|
3 | Q4Q2Y5 (/ISO) Q584D7 (/ISO) Q584D7 (/ISO) |
|
Regulation of eIF2 alpha phosphorylation by heme GO:0010999
Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels.
|
3 | Q4Q2Y5 (/ISO) Q584D7 (/ISO) Q584D7 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
3 | Q4Q2Y5 (/ISO) Q584D7 (/ISO) Q584D7 (/ISO) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | Q4Q2Y5 (/ISA) Q584D7 (/ISA) Q584D7 (/ISA) |
|
Perinuclear endoplasmic reticulum membrane GO:1990578
The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus.
|
3 | Q4Q2Y5 (/ISO) Q584D7 (/ISO) Q584D7 (/ISO) |