The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transcription elongation factor S-II, central domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Transcription elongation factor S-II

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
8 P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI)
RNA polymerase II regulatory region DNA binding GO:0001012
Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase II. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
8 P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA)
RNA polymerase II complex recruiting activity GO:0001139
Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
8 P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI) P07273 (/IPI)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter GO:0001193
Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter.
8 P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI)
Maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter GO:0001193
Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter.
8 P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP)
Transcription elongation from RNA polymerase I promoter GO:0006362
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I.
8 P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
8 P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
8 P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
8 P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
8 P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA)
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
8 P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP)
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
8 P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA)
Regulation of mRNA 3'-end processing GO:0031440
Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
8 P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI) P07273 (/IGI)
Regulation of mRNA 3'-end processing GO:0031440
Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
8 P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP)
Transcription antitermination GO:0031564
Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond termination site(s).
8 P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA)
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
8 P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA)
TRNA transcription by RNA polymerase III GO:0042797
The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.
8 P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP)
Positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0045899
Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.
8 P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA)
Positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0045899
Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.
8 P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP) P07273 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA) P07273 (/IDA)