The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cyclin-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Transcription initiation factor IIB

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 34 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
100 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(90 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
100 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(90 more)
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
99 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(89 more)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
99 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(89 more)
RNA polymerase II core promoter sequence-specific DNA binding GO:0000979
Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.
95 P29054 (/ISS) P29054 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS) Q2KIN8 (/ISS) Q4R3J5 (/ISS) Q4R3J5 (/ISS)
(85 more)
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
95 P29054 (/ISS) P29054 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS) Q2KIN8 (/ISS) Q4R3J5 (/ISS) Q4R3J5 (/ISS)
(85 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
56 O13749 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI)
(46 more)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
53 P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI) P29052 (/IPI)
(43 more)
RNA polymerase II core promoter sequence-specific DNA binding GO:0000979
Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.
48 P62915 (/IDA) P62915 (/IDA) P62915 (/IDA) P62915 (/IDA) P62915 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(38 more)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
45 P29055 (/IDA) P29055 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(35 more)
TBP-class protein binding GO:0017025
Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).
45 P29055 (/IPI) P29055 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI)
(35 more)
RNA polymerase II general transcription initiation factor activity GO:0016251
An activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase II. The general transcription factors for RNA polymerase II include TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBP).
44 O13749 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(34 more)
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
Thyroid hormone receptor binding GO:0046966
Interacting selectively and non-covalently with a thyroid hormone receptor.
43 Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI) Q00403 (/IPI)
(33 more)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
RNA polymerase II core promoter sequence-specific DNA binding GO:0000979
Interacting selectively and non-covalently with a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
5 P62915 (/IDA) P62915 (/IDA) P62915 (/IDA) P62915 (/IDA) P62915 (/IDA)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
RNA polymerase II general transcription initiation factor activity GO:0016251
An activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase II. The general transcription factors for RNA polymerase II include TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBP).
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
TBP-class protein binding GO:0017025
Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Thyroid hormone receptor binding GO:0046966
Interacting selectively and non-covalently with a thyroid hormone receptor.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
2 P29055 (/IPI) P29055 (/IPI)
RNA polymerase II complex recruiting activity GO:0001139
Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
2 P29055 (/IDA) P29055 (/IDA)
RNA polymerase II complex recruiting activity GO:0001139
Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
2 P29055 (/IMP) P29055 (/IMP)
TBP-class protein binding GO:0017025
Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).
2 P29055 (/IDA) P29055 (/IDA)
TBP-class protein binding GO:0017025
Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).
2 P29055 (/IMP) P29055 (/IMP)
RNA polymerase II complex recruiting activity GO:0001139
Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
1 Q54FD6 (/ISS)

There are 38 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
110 P29052 (/ISS) P29052 (/ISS) P29052 (/ISS) P29052 (/ISS) P29052 (/ISS) P29052 (/ISS) P29052 (/ISS) P29052 (/ISS) P29052 (/ISS) P29052 (/ISS)
(100 more)
Transcriptional start site selection at RNA polymerase II promoter GO:0001174
Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
100 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(90 more)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
100 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(90 more)
RNA polymerase II preinitiation complex assembly GO:0051123
The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
100 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(90 more)
Positive regulation of transcription initiation from RNA polymerase II promoter GO:0060261
Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
100 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(90 more)
RNA polymerase II core complex assembly GO:1990114
The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.
100 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(90 more)
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
99 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(89 more)
Positive regulation by host of viral transcription GO:0043923
Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
99 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(89 more)
RNA polymerase II preinitiation complex assembly GO:0051123
The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
46 O13749 (/IDA) P29055 (/IDA) P29055 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(36 more)
Transcriptional start site selection at RNA polymerase II promoter GO:0001174
Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
45 P29055 (/IMP) P29055 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP)
(35 more)
RNA polymerase II preinitiation complex assembly GO:0051123
The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
45 P29055 (/IMP) P29055 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP)
(35 more)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
44 O13749 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(34 more)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
43 Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP)
(33 more)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
43 Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS)
(33 more)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
43 Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS)
(33 more)
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
43 Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS)
(33 more)
Positive regulation by host of viral transcription GO:0043923
Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
Positive regulation of viral transcription GO:0050434
Any process that activates or increases the frequency, rate or extent of viral transcription.
43 Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP)
(33 more)
Positive regulation of transcription initiation from RNA polymerase II promoter GO:0060261
Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
43 Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP)
(33 more)
Positive regulation of core promoter binding GO:1904798
Any process that activates or increases the frequency, rate or extent of core promoter binding.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
RNA polymerase II core complex assembly GO:1990114
The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.
43 Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP)
(33 more)
Transcriptional start site selection at RNA polymerase II promoter GO:0001174
Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
10 P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
10 P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA)
Regulation of DNA binding GO:0051101
Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
10 P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA)
Transcriptional start site selection at RNA polymerase II promoter GO:0001174
Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Protein acetylation GO:0006473
The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Positive regulation by host of viral transcription GO:0043923
Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Positive regulation of viral transcription GO:0050434
Any process that activates or increases the frequency, rate or extent of viral transcription.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
RNA polymerase II preinitiation complex assembly GO:0051123
The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Positive regulation of transcription initiation from RNA polymerase II promoter GO:0060261
Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Positive regulation of core promoter binding GO:1904798
Any process that activates or increases the frequency, rate or extent of core promoter binding.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
RNA polymerase II core complex assembly GO:1990114
The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Transcriptional open complex formation at RNA polymerase II promoter GO:0001113
Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
2 P29055 (/IMP) P29055 (/IMP)
Positive regulation of transcription regulatory region DNA binding GO:2000679
Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.
2 P29055 (/IDA) P29055 (/IDA)

There are 20 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
100 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(90 more)
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
99 P29054 (/ISS) P29054 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62915 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS)
(89 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
95 P29054 (/ISS) P29054 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS) P62916 (/ISS) Q2KIN8 (/ISS) Q4R3J5 (/ISS) Q4R3J5 (/ISS)
(85 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
60 P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA) P29052 (/IDA)
(50 more)
Transcriptional preinitiation complex GO:0097550
A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.
45 P29055 (/IDA) P29055 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(35 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
43 Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS) Q00403 (/TAS)
(33 more)
Transcription factor TFIID complex GO:0005669
A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
43 Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA) Q00403 (/IDA)
(33 more)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
43 Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP) Q00403 (/IMP)
(33 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Transcription factor TFIID complex GO:0005669
A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Transcriptional preinitiation complex GO:0097550
A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.
5 P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO) P62915 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O13749 (/HDA)