The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ncd80 complex, Nuf2 subunit
".
FunFam 1: NDC80 kinetochore complex component NUF2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
11 |
Q76I90 (/IPI)
Q9BZD4 (/IPI)
Q9BZD4 (/IPI)
Q9BZD4 (/IPI)
Q9BZD4 (/IPI)
Q9BZD4 (/IPI)
Q9BZD4 (/IPI)
Q9BZD4 (/IPI)
Q9BZD4 (/IPI)
Q9BZD4 (/IPI)
(1 more) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
|
10 | Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) |
|
Attachment of spindle microtubules to kinetochore GO:0008608
The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.
|
1 | Q99P69 (/ISO) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
28 |
B1AQT3 (/IDA)
B1AQT3 (/IDA)
B1AQT3 (/IDA)
B1AQT4 (/IDA)
B1AQT4 (/IDA)
B1AQT4 (/IDA)
E9PKH1 (/IDA)
E9PKH1 (/IDA)
E9PQC4 (/IDA)
E9PQC4 (/IDA)
(18 more) |
|
Chromosome, centromeric region GO:0000775
The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
10 | Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) Q9BZD4 (/NAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
10 | Q9BZD4 (/TAS) Q9BZD4 (/TAS) Q9BZD4 (/TAS) Q9BZD4 (/TAS) Q9BZD4 (/TAS) Q9BZD4 (/TAS) Q9BZD4 (/TAS) Q9BZD4 (/TAS) Q9BZD4 (/TAS) Q9BZD4 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
10 | Q9BZD4 (/HDA) Q9BZD4 (/HDA) Q9BZD4 (/HDA) Q9BZD4 (/HDA) Q9BZD4 (/HDA) Q9BZD4 (/HDA) Q9BZD4 (/HDA) Q9BZD4 (/HDA) Q9BZD4 (/HDA) Q9BZD4 (/HDA) |
|
Ndc80 complex GO:0031262
An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.
|
10 | Q9BZD4 (/IDA) Q9BZD4 (/IDA) Q9BZD4 (/IDA) Q9BZD4 (/IDA) Q9BZD4 (/IDA) Q9BZD4 (/IDA) Q9BZD4 (/IDA) Q9BZD4 (/IDA) Q9BZD4 (/IDA) Q9BZD4 (/IDA) |
|
Ndc80 complex GO:0031262
An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.
|
3 | Q6AYL9 (/ISS) Q76I90 (/ISS) Q99P69 (/ISS) |
|
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
1 | Q99P69 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q99P69 (/ISO) |
|
Ndc80 complex GO:0031262
An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.
|
1 | Q99P69 (/ISO) |