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CATH Superfamily 1.10.40.30

Fumarase/aspartase (C-terminal domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (C-terminal domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Argininosuccinate lyase. [EC: 4.3.2.1]
2-(N(omega)-L-arginino)succinate = fumarate + L-arginine.
    		 1172 A0A009H513 A0A009IQ92 A0A009KHA8 A0A009QBM3 A0A009RZI7 A0A009S4S8 A0A015S9I7 A0A015S9V3 A0A015SZZ4 A0A015TUT2
    (1162 more...)
    Fumarate hydratase. [EC: 4.2.1.2]
    (S)-malate = fumarate + H(2)O.
      		 371 A0A023YXT3 A0A024L3D9 A0A025CPX0 A0A026UFK2 A0A029HY77 A0A029ISD1 A0A045IXZ8 A0A061YP04 A0A063UR14 A0A069XKU3
      (361 more...)
      Aspartate ammonia-lyase. [EC: 4.3.1.1]
      L-aspartate = fumarate + NH(3).
        		 159 A0A023Z6W2 A0A025CKY4 A0A026UQH8 A0A027ZCY3 A0A029HCB4 A0A029IGN9 A0A069XW52 A0A070FAZ9 A0A070UKE9 A0A072ZFI1
        (149 more...)
        Adenylosuccinate lyase. [EC: 4.3.2.2]
        (1) N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP. (2) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamide.
        • Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole.
        		 153 A0A023YW56 A0A025CAL9 A0A069XS62 A0A070SQY6 A0A070UH39 A0A073HJ32 A0A073UYV2 A0A075WJ34 A0A0D1G9L3 A0A0E0VQF1
        (143 more...)
        3-carboxy-cis,cis-muconate cycloisomerase. [EC: 5.5.1.2]
        2-carboxy-2,5-dihydro-5-oxofuran-2-acetate = cis,cis-butadiene-1,2,4- tricarboxylate.
          		 4 O31385 P32427 Q59092 Q9I6Q8
          Amino-acid N-acetyltransferase. [EC: 2.3.1.1]
          Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate.
          • Also acts with L-aspartate and, more slowly, with some other amino acids.
          		 2 Q9K3D6 Q9K3D7