The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"acid-sensing ion channel 1 domain
".
FunFam 4: Acid-sensing ion channel 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
3 | Q6X1Y6 (/TAS) Q9UHC3 (/TAS) Q9UHC3 (/TAS) |
Sodium channel activity GO:0005272
Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
2 | Q9UHC3 (/TAS) Q9UHC3 (/TAS) |
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
1 | Q6X1Y6 (/IDA) |
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
1 | Q6X1Y6 (/IMP) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O35240 (/IPI) |
Ligand-gated sodium channel activity GO:0015280
Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
|
1 | O35240 (/IDA) |
Ligand-gated sodium channel activity GO:0015280
Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
|
1 | O35240 (/IMP) |
Ligand-gated sodium channel activity GO:0015280
Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
|
1 | Q6X1Y6 (/ISO) |
Enterobactin transmembrane transporter activity GO:0042931
Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other.
|
1 | Q6X1Y6 (/IMP) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
2 | Q9UHC3 (/TAS) Q9UHC3 (/TAS) |
Sensory perception GO:0007600
The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
|
2 | Q9UHC3 (/TAS) Q9UHC3 (/TAS) |
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
2 | O35240 (/IDA) Q6X1Y6 (/IDA) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
2 | Q9UHC3 (/TAS) Q9UHC3 (/TAS) |
Sensory perception of sour taste GO:0050915
The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
|
2 | Q9UHC3 (/IMP) Q9UHC3 (/IMP) |
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q6X1Y6 (/IDA) |
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q6X1Y6 (/IMP) |
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O35240 (/IDA) |
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O35240 (/IMP) |
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q6X1Y6 (/ISO) |
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | Q6X1Y6 (/IMP) |
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
1 | Q6X1Y6 (/IMP) |
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
1 | Q6X1Y6 (/IMP) |
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
1 | Q6X1Y6 (/ISO) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
1 | O35240 (/IDA) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
1 | Q6X1Y6 (/IMP) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
1 | Q6X1Y6 (/ISO) |
Detection of chemical stimulus involved in sensory perception GO:0050907
The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.
|
1 | Q6X1Y6 (/IMP) |
Sensory perception of sour taste GO:0050915
The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
|
1 | Q6X1Y6 (/ISO) |
Detection of temperature stimulus involved in sensory perception GO:0050961
The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception.
|
1 | Q6X1Y6 (/IMP) |
Detection of temperature stimulus involved in sensory perception of pain GO:0050965
The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.
|
1 | Q6X1Y6 (/IMP) |
Detection of mechanical stimulus involved in sensory perception of pain GO:0050966
The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.
|
1 | Q6X1Y6 (/IMP) |
Detection of chemical stimulus involved in sensory perception of pain GO:0050968
The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.
|
1 | Q6X1Y6 (/IMP) |
Detection of mechanical stimulus involved in sensory perception GO:0050974
The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.
|
1 | Q6X1Y6 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9UHC3 (/TAS) Q9UHC3 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | O35240 (/IDA) Q6X1Y6 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9UHC3 (/TAS) Q9UHC3 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O35240 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q6X1Y6 (/ISO) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q6X1Y6 (/ISO) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | O35240 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q6X1Y6 (/ISO) |