The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"acid-sensing ion channel 1 domain
".
FunFam 2: acid-sensing ion channel 1 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 17 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
18 |
P78348 (/IPI)
P78348 (/IPI)
P78348 (/IPI)
P78348 (/IPI)
P78348 (/IPI)
P78348 (/IPI)
P78348 (/IPI)
P78348 (/IPI)
P78348 (/IPI)
P78348 (/IPI)
(8 more) |
Acid-sensing ion channel activity GO:0044736
Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex.
|
17 |
P55926 (/ISS)
P55926 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
(7 more) |
Acid-sensing ion channel activity GO:0044736
Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex.
|
14 |
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
(4 more) |
Ligand-gated sodium channel activity GO:0015280
Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
|
13 |
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
(3 more) |
Ion channel activity GO:0005216
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
|
5 | P55926 (/IDA) P55926 (/IDA) Q62962 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Ligand-gated sodium channel activity GO:0015280
Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
|
4 | Q708S7 (/IDA) Q708S7 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Ion channel activity GO:0005216
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
|
3 | Q6NXK8 (/ISO) Q925H0 (/ISO) Q925H0 (/ISO) |
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
3 | Q6NXK8 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
3 | Q6NXK8 (/IMP) Q925H0 (/IMP) Q925H0 (/IMP) |
Ion gated channel activity GO:0022839
Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.
|
3 | Q6NXK8 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Ion gated channel activity GO:0022839
Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.
|
3 | Q6NXK8 (/IMP) Q925H0 (/IMP) Q925H0 (/IMP) |
Voltage-gated sodium channel activity GO:0005248
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
2 | Q925H0 (/ISO) Q925H0 (/ISO) |
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
2 | Q708S7 (/IGI) Q708S7 (/IGI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q1XA76 (/IPI) Q1XA76 (/IPI) |
Voltage-gated sodium channel activity GO:0005248
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q62962 (/IDA) |
Monovalent inorganic cation transmembrane transporter activity GO:0015077
Enables the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
|
1 | Q6NXK8 (/ISO) |
Acid-sensing ion channel activity GO:0044736
Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex.
|
1 | Q6NXK8 (/ISO) |
There are 53 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
|
17 |
P55926 (/ISS)
P55926 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
(7 more) |
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
15 |
P55926 (/ISS)
P55926 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
(5 more) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
13 |
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
(3 more) |
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
13 |
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
(3 more) |
Sensory perception of sour taste GO:0050915
The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
|
13 |
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
(3 more) |
Cellular response to pH GO:0071467
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
|
13 |
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
(3 more) |
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
11 |
P78348 (/NAS)
P78348 (/NAS)
P78348 (/NAS)
P78348 (/NAS)
P78348 (/NAS)
P78348 (/NAS)
P78348 (/NAS)
P78348 (/NAS)
P78348 (/NAS)
P78348 (/NAS)
(1 more) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
11 |
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
(1 more) |
Response to pH GO:0009268
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
|
11 |
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
(1 more) |
Cellular response to pH GO:0071467
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
|
6 | P55926 (/ISS) P55926 (/ISS) Q6NXK8 (/ISS) Q708S7 (/ISS) Q708S7 (/ISS) Q7T1N4 (/ISS) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
5 | P55926 (/IMP) P55926 (/IMP) Q6NXK8 (/IMP) Q925H0 (/IMP) Q925H0 (/IMP) |
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | Q6NXK8 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | Q6NXK8 (/IMP) Q925H0 (/IMP) Q925H0 (/IMP) |
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | Q62962 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
3 | Q6NXK8 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
3 | Q6NXK8 (/IMP) Q925H0 (/IMP) Q925H0 (/IMP) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
3 | Q6NXK8 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
3 | Q6NXK8 (/IMP) Q925H0 (/IMP) Q925H0 (/IMP) |
Sensory perception of sour taste GO:0050915
The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
|
3 | Q6NXK8 (/ISO) Q925H0 (/ISO) Q925H0 (/ISO) |
Regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback GO:0003026
The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q925H0 (/ISO) Q925H0 (/ISO) |
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
2 | Q16515 (/TAS) Q16515 (/TAS) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
2 | Q16515 (/TAS) Q16515 (/TAS) |
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
|
2 | Q16515 (/TAS) Q16515 (/TAS) |
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Monovalent inorganic cation transport GO:0015672
The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
|
2 | Q16515 (/TAS) Q16515 (/TAS) |
Regulation of vasoconstriction GO:0019229
Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
|
2 | P55926 (/NAS) P55926 (/NAS) |
Regulation of ion transmembrane transport GO:0034765
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Protein localization to synapse GO:0035418
Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
2 | Q925H0 (/ISO) Q925H0 (/ISO) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Response to steroid hormone GO:0048545
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
|
2 | Q708S5 (/IEP) Q708S5 (/IEP) |
Detection of mechanical stimulus involved in sensory perception GO:0050974
The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
2 | Q925H0 (/IMP) Q925H0 (/IMP) |
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
|
2 | Q1XA76 (/IDA) Q1XA76 (/IDA) |
Cellular response to acidic pH GO:0071468
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
2 | Q925H0 (/ISO) Q925H0 (/ISO) |
Positive regulation of cation channel activity GO:2001259
Any process that activates or increases the frequency, rate or extent of cation channel activity.
|
2 | Q925H0 (/ISO) Q925H0 (/ISO) |
Behavioral fear response GO:0001662
An acute behavioral change resulting from a perceived external threat.
|
1 | Q6NXK8 (/IMP) |
Response to amphetamine GO:0001975
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
|
1 | Q6NXK8 (/IMP) |
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
|
1 | Q6NXK8 (/IMP) |
Associative learning GO:0008306
Learning by associating a stimulus (the cause) with a particular outcome (the effect).
|
1 | Q6NXK8 (/IMP) |
Monovalent inorganic cation transport GO:0015672
The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
|
1 | Q6NXK8 (/ISO) |
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
1 | Q6NXK8 (/ISO) |
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q62962 (/IDA) |
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q6NXK8 (/ISO) |
Negative regulation of neurotransmitter secretion GO:0046929
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
|
1 | Q6NXK8 (/IMP) |
Calcium ion transmembrane transport GO:0070588
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q6NXK8 (/IMP) |
Cellular response to pH GO:0071467
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
|
1 | Q6NXK8 (/ISO) |
Cellular response to acidic pH GO:0071468
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
1 | Q62962 (/IDA) |
Positive regulation of cation channel activity GO:2001259
Any process that activates or increases the frequency, rate or extent of cation channel activity.
|
1 | Q62962 (/IDA) |
There are 21 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
14 |
P55926 (/ISS)
P55926 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
P78348 (/ISS)
(4 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
13 |
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
(3 more) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
13 |
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
P78348 (/IMP)
(3 more) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
13 |
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
P78348 (/TAS)
(3 more) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
11 |
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
(1 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
11 |
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
P78348 (/IDA)
(1 more) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | Q6NXK8 (/IDA) Q708S7 (/IDA) Q708S7 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
3 | Q6NXK8 (/IDA) Q925H0 (/IDA) Q925H0 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | P55926 (/IDA) P55926 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q925H0 (/IDA) Q925H0 (/IDA) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
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2 | Q925H0 (/IDA) Q925H0 (/IDA) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
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2 | Q925H0 (/IDA) Q925H0 (/IDA) |
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
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2 | Q925H0 (/IDA) Q925H0 (/IDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
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1 | Q6NXK8 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
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1 | Q6NXK8 (/ISO) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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1 | Q6NXK8 (/ISO) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
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1 | Q6NXK8 (/ISO) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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1 | Q6NXK8 (/ISO) |
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
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1 | Q6NXK8 (/ISO) |
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
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1 | Q6NXK8 (/ISO) |
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
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1 | Q6NXK8 (/ISO) |