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CATH Superfamily 1.10.357.140

UbiA prenyltransferase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
UbiA prenyltransferase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: 4-hydroxybenzoate polyprenyltransferase, mitochond...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
4-hydroxybenzoate polyprenyltransferase. [EC: 2.5.1.39]
A polyprenyl diphosphate + 4-hydroxybenzoate = diphosphate + a 4-hydroxy- 3-polyprenylbenzoate.
  • This enzyme, involved in the biosynthesis of ubiquinone, attaches a polyprenyl side chain to a 4-hydroxybenzoate ring, producing the first ubiquinone intermediate that is membrane bound.
  • The number of isoprenoid subunits in the side chain varies in different species.
  • The enzyme does not have any specificity concerning the length of the polyprenyl tail, and accepts tails of various lengths with similar efficiency.
 18 A0A0R3NH06 A0A0R3NH06 N1NWU7 N1NWU7 P32378 P32378 Q10252 Q16QL3 Q298G6 Q298G6
(8 more...)
4-hydroxybenzoate geranyltransferase. [EC: 2.5.1.93]
Geranyl diphosphate + 4-hydroxybenzoate = 3-geranyl-4-hydroxybenzoate + diphosphate.
  • The enzyme is involved in shikonin biosynthesis.
  • It has a strict substrate specificity for geranyl diphosphate.
 2 Q8W404 Q8W405