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CATH Superfamily 1.10.3330.10

Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: 2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OH...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. [EC: 4.1.1.97]
5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate = (S)- allantoin + CO(2).
  • This enzyme is part of the pathway from urate to (S)-allantoin, which is present in bacteria, plants and animals (but not in humans).
  • Formerly EC 4.1.1.n1.
 16 A0A164TNZ2 A0A164TNZ2 A0A164TNZ2 A0A164TNZ2 A0A1B2AYV6 A0A1B2AYV6 A0A1B2AYV6 A0A1B2AYV6 L8ATQ3 L8ATQ3
(6 more...)
Factor independent urate hydroxylase. [EC: 1.7.3.3]
Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2).
  • Was previously thought to be a copper protein, but it is now known that the enzymes from soybean (Glycine max), the mold Aspergillus flavus and Bacillus subtilis contains no copper nor any other transition-metal ion.
  • The 5-hydroxyisourate formed decomposes spontaneously to form allantoin and CO(2), although there is an enzyme-catalyzed pathway in which EC 3.5.2.17 catalyzes the first step.
  • The enzyme is different from EC 1.14.13.113.
 16 A0A164TNZ2 A0A164TNZ2 A0A164TNZ2 A0A164TNZ2 A0A1B2AYV6 A0A1B2AYV6 A0A1B2AYV6 A0A1B2AYV6 L8ATQ3 L8ATQ3
(6 more...)