The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Clc chloride channel
".
FunFam 11: Chloride channel protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chloride channel activity GO:0005254
Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
3 | Q8IQN2 (/ISS) Q8MQK2 (/ISS) Q9VUY1 (/ISS) |
|
Chloride transmembrane transporter activity GO:0015108
Enables the transfer of chloride ions from one side of a membrane to the other.
|
3 | Q8IQN2 (/IMP) Q8MQK2 (/IMP) Q9VUY1 (/IMP) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Renal system process GO:0003014
A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).
|
3 | Q8IQN2 (/IEP) Q8MQK2 (/IEP) Q9VUY1 (/IEP) |
|
Endosomal lumen acidification GO:0048388
Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion.
|
3 | Q8IQN2 (/IMP) Q8MQK2 (/IMP) Q9VUY1 (/IMP) |
|
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
|
3 | Q8IQN2 (/IMP) Q8MQK2 (/IMP) Q9VUY1 (/IMP) |
|
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
|
3 | Q8IQN2 (/ISS) Q8MQK2 (/ISS) Q9VUY1 (/ISS) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
3 | Q8IQN2 (/IDA) Q8MQK2 (/IDA) Q9VUY1 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | Q8IQN2 (/ISS) Q8MQK2 (/ISS) Q9VUY1 (/ISS) |
|
Recycling endosome GO:0055037
An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.
|
3 | Q8IQN2 (/IDA) Q8MQK2 (/IDA) Q9VUY1 (/IDA) |