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CATH Superfamily 1.10.3060.10

Helical scaffold and wing domains of SecA

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Helical scaffold and wing domains of SecA
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Preprotein translocase subunit SecA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 58 P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI)
(48 more)
ATPase-coupled protein transmembrane transporter activity GO:0015462
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).
 58 P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA)
(48 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 58 P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI) P10408 (/IPI)
(48 more)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein targeting GO:0006605
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
 58 P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP)
(48 more)
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 58 P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP)
(48 more)
Protein transport by the Sec complex GO:0043952
The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.
 58 P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA)
(48 more)
Protein transport by the Sec complex GO:0043952
The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.
 58 P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP)
(48 more)
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
 58 P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA)
(48 more)
Intracellular protein transmembrane transport GO:0065002
The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
 58 P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP) P10408 (/IMP)
(48 more)
Protein secretion GO:0009306
The controlled release of proteins from a cell.
 7 Q9KPH4 (/ISS) Q9KPH4 (/ISS) Q9KPH4 (/ISS) Q9KPH4 (/ISS) Q9KPH4 (/ISS) Q9KPH4 (/ISS) Q9KPH4 (/ISS)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 58 P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA)
(48 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 58 P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA)
(48 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 58 P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA)
(48 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 58 P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA)
(48 more)
Cell envelope Sec protein transport complex GO:0031522
A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.
 58 P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA) P10408 (/IDA)
(48 more)