CATH Superfamily 1.10.287.70
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 76: Potassium channel subfamily K member
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
11 |
A5PLK0 (/IDA)
B8A573 (/IDA)
E9QGL8 (/IDA)
O00180 (/IDA)
O00180 (/IDA)
O00180 (/IDA)
O00180 (/IDA)
O00180 (/IDA)
O00180 (/IDA)
O00180 (/IDA)
(1 more) |
|
Potassium ion leak channel activity GO:0022841
Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
|
8 | O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) Q9Z2T2 (/IDA) |
|
Inward rectifier potassium channel activity GO:0005242
Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.
|
7 | O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) |
|
Sodium channel activity GO:0005272
Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
7 | O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
7 | O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) O00180 (/IPI) |
|
Sodium channel activity GO:0005272
Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
6 | O08581 (/ISS) Q0P5A0 (/ISS) Q5RD07 (/ISS) Q5UE96 (/ISS) Q8R454 (/ISS) Q9Z2T2 (/ISS) |
|
Potassium ion leak channel activity GO:0022841
Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
|
6 | O08581 (/ISS) Q0P5A0 (/ISS) Q5RD07 (/ISS) Q5UE96 (/ISS) Q8R454 (/ISS) Q9Z2T2 (/ISS) |
|
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
5 | Q0P5A0 (/ISS) Q5RD07 (/ISS) Q5UE96 (/ISS) Q8R454 (/ISS) Q9Z2T2 (/ISS) |
|
Outward rectifier potassium channel activity GO:0015271
Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.
|
2 | A5PLK0 (/IDA) E9QGL8 (/IDA) |
|
Inward rectifier potassium channel activity GO:0005242
Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.
|
1 | O08581 (/IDA) |
|
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | O08581 (/ISO) |
|
Sodium channel activity GO:0005272
Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | O08581 (/ISO) |
|
Potassium ion leak channel activity GO:0022841
Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
|
1 | O08581 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | O08581 (/ISO) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
9 | O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O08581 (/IDA) Q9Z2T2 (/IDA) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
7 | O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
7 | O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) |
|
Regulation of resting membrane potential GO:0060075
Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.
|
7 | O00180 (/IMP) O00180 (/IMP) O00180 (/IMP) O00180 (/IMP) O00180 (/IMP) O00180 (/IMP) O00180 (/IMP) |
|
Cardiac conduction GO:0061337
Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.
|
7 | O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
6 | O08581 (/ISS) Q0P5A0 (/ISS) Q5RD07 (/ISS) Q5UE96 (/ISS) Q8R454 (/ISS) Q9Z2T2 (/ISS) |
|
Regulation of resting membrane potential GO:0060075
Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.
|
6 | O08581 (/ISS) Q0P5A0 (/ISS) Q5RD07 (/ISS) Q5UE96 (/ISS) Q8R454 (/ISS) Q9Z2T2 (/ISS) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
5 | Q0P5A0 (/ISS) Q5RD07 (/ISS) Q5UE96 (/ISS) Q8R454 (/ISS) Q9Z2T2 (/ISS) |
|
Heart process GO:0003015
A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
3 | A5PLK0 (/IGI) B8A573 (/IGI) E9QGL8 (/IGI) |
|
Heart process GO:0003015
A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
3 | A5PLK0 (/IMP) B8A573 (/IMP) E9QGL8 (/IMP) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O08581 (/IC) |
|
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
|
1 | Q9Z2T2 (/IEP) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | O08581 (/ISO) |
|
Regulation of resting membrane potential GO:0060075
Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.
|
1 | O08581 (/ISO) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
1 | O08581 (/ISO) |
There are 22 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
14 |
A0A024R3T2 (/IDA)
A0A024R3T2 (/IDA)
A0A024R3T2 (/IDA)
A0A024R3T2 (/IDA)
A0A024R3T2 (/IDA)
A0A024R3T2 (/IDA)
A0A024R3T2 (/IDA)
O00180 (/IDA)
O00180 (/IDA)
O00180 (/IDA)
(4 more) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
12 |
O00180 (/ISS)
O00180 (/ISS)
O00180 (/ISS)
O00180 (/ISS)
O00180 (/ISS)
O00180 (/ISS)
O00180 (/ISS)
Q0P5A0 (/ISS)
Q5RD07 (/ISS)
Q5UE96 (/ISS)
(2 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
7 | O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
7 | O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) O00180 (/TAS) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
7 | O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) |
|
Potassium channel complex GO:0034705
An ion channel complex through which potassium ions pass.
|
7 | O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) O00180 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | O08581 (/ISS) Q0P5A0 (/ISS) Q5RD07 (/ISS) Q5UE96 (/ISS) Q8R454 (/ISS) Q9Z2T2 (/ISS) |
|
Potassium channel complex GO:0034705
An ion channel complex through which potassium ions pass.
|
6 | O08581 (/ISS) Q0P5A0 (/ISS) Q5RD07 (/ISS) Q5UE96 (/ISS) Q8R454 (/ISS) Q9Z2T2 (/ISS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | O08581 (/IMP) Q9Z2T2 (/IMP) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9Z2T2 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O08581 (/ISO) |
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
1 | O08581 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | O08581 (/ISO) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | O08581 (/ISO) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q9Z2T2 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | O08581 (/ISO) |
|
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
|
1 | Q9Z2T2 (/IDA) |
|
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
|
1 | O08581 (/ISO) |
|
Potassium channel complex GO:0034705
An ion channel complex through which potassium ions pass.
|
1 | O08581 (/ISO) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | O08581 (/ISO) |
|
Inward rectifier potassium channel complex GO:1902937
A protein complex which is capable of inward rectifier potassium channel activity.
|
1 | O08581 (/IDA) |