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CATH Superfamily 1.10.287.40

Serine-tRNA synthetase, tRNA binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Serine-tRNA synthetase, tRNA binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Serine--tRNA ligase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
 172 P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA)
(162 more)
Serine-tRNA ligase activity GO:0004828
Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).
 172 P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA)
(162 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 172 P0A8L1 (/IPI) P0A8L1 (/IPI) P0A8L1 (/IPI) P0A8L1 (/IPI) P0A8L1 (/IPI) P0A8L1 (/IPI) P0A8L1 (/IPI) P0A8L1 (/IPI) P0A8L1 (/IPI) P0A8L1 (/IPI)
(162 more)
Serine-tRNA ligase activity GO:0004828
Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).
 11 Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS)
(1 more)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Seryl-tRNA aminoacylation GO:0006434
The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA.
 172 P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA)
(162 more)
Selenocysteine biosynthetic process GO:0016260
The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins.
 172 P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA)
(162 more)
Seryl-tRNA aminoacylation GO:0006434
The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA.
 11 Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS) Q9KSZ6 (/ISS)
(1 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 172 P0A8L1 (/HDA) P0A8L1 (/HDA) P0A8L1 (/HDA) P0A8L1 (/HDA) P0A8L1 (/HDA) P0A8L1 (/HDA) P0A8L1 (/HDA) P0A8L1 (/HDA) P0A8L1 (/HDA) P0A8L1 (/HDA)
(162 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 172 P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA) P0A8L1 (/IDA)
(162 more)