The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: UXT isoform 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
11 Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA)
(1 more)
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
11 Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
11 Q9UBK9 (/IPI) Q9UBK9 (/IPI) Q9UBK9 (/IPI) Q9UBK9 (/IPI) Q9UBK9 (/IPI) Q9UBK9 (/IPI) Q9UBK9 (/IPI) Q9UBK9 (/IPI) Q9UBK9 (/IPI) Q9UBK9 (/IPI)
(1 more)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
11 Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS)
(1 more)
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
11 Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA)
(1 more)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
3 Q32P97 (/ISS) Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
3 Q32P97 (/ISS) Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
2 Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q9WTZ0 (/ISO)
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
1 Q9WTZ0 (/ISO)
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
1 Q9WTZ0 (/ISO)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
11 Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA)
(1 more)
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
11 Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP)
(1 more)
Centrosome cycle GO:0007098
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
11 Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP) Q9UBK9 (/IMP)
(1 more)
Mitochondrion transport along microtubule GO:0047497
The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
11 Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS)
(1 more)
Negative regulation of G0 to G1 transition GO:0070317
A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.
11 Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS)
(1 more)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 Q32P97 (/ISS) Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
2 Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Centrosome cycle GO:0007098
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
2 Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q9WTZ0 (/ISO)
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
1 Q9WTZ0 (/ISO)
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
1 Q66IA7 (/IMP)
Centrosome cycle GO:0007098
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
1 Q9WTZ0 (/ISO)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q66IA7 (/IMP)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
11 Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA)
(1 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
11 Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS) Q9UBK9 (/TAS)
(1 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
11 Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA)
(1 more)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
11 Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA)
(1 more)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
11 Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA) Q9UBK9 (/IDA)
(1 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q32P97 (/ISS) Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q32P97 (/ISS) Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
2 Q63ZY7 (/ISS) Q9WTZ0 (/ISS)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
1 Q66IA7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9WTZ0 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9WTZ0 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 Q9WTZ0 (/ISO)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
1 Q9WTZ0 (/ISO)