The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Prefoldin subunit 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
19 Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI)
(9 more)
Protein folding chaperone GO:0044183
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
19 Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI) Q9UHV9 (/IPI)
(9 more)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
19 Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS)
(9 more)
Protein folding chaperone GO:0044183
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
1 O70591 (/ISO)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
19 Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS)
(9 more)
Positive regulation of cytoskeleton organization GO:0051495
Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
19 Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA)
(9 more)
Establishment or maintenance of neuroblast polarity GO:0045196
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
2 Q9VTE5 (/IMP) Q9VTE5 (/IMP)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
1 O70591 (/IDA)
Tubulin complex assembly GO:0007021
The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer.
1 Q9UTC9 (/ISS)
Positive regulation of cytoskeleton organization GO:0051495
Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
1 O70591 (/ISO)
Positive regulation of cytoskeleton organization GO:0051495
Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
1 Q55GN3 (/ISS)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
38 B1AQP2 (/IDA) B1AQP2 (/IDA) B1AQP2 (/IDA) B1AQP2 (/IDA) B1AQP2 (/IDA) B1AQP2 (/IDA) B1AQP2 (/IDA) B1AQP2 (/IDA) B1AQP2 (/IDA) B1AQP2 (/IDA)
(28 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
20 Q382R3 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA)
(10 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
19 Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA)
(9 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
19 Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA) Q9UHV9 (/IDA)
(9 more)
Prefoldin complex GO:0016272
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
19 Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS) Q9UHV9 (/NAS)
(9 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 A1A4P5 (/TAS) A1A4P5 (/TAS) A1A4P5 (/TAS) A1A4P5 (/TAS) A1A4P5 (/TAS) O70591 (/TAS)
Prefoldin complex GO:0016272
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
2 Q9VTE5 (/IDA) Q9VTE5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O70591 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O70591 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 O70591 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O70591 (/ISO)
Prefoldin complex GO:0016272
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
1 Q9UTC9 (/ISS)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q382R3 (/IDA)