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CATH Superfamily 1.10.287.130

Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Sensor histidine kinase CpxA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 212 A0A0H3NUZ2 (/IPI) A0A0H3NUZ2 (/IPI) A0A0H3NUZ2 (/IPI) A0A0H3NUZ2 (/IPI) A0A0H3NUZ2 (/IPI) A0A0H3NUZ2 (/IPI) A0A0H3NUZ2 (/IPI) A0A0H3NUZ2 (/IPI) A0A0H3NUZ2 (/IPI) A0A0H3NUZ2 (/IPI)
(202 more)
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
 130 P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA)
(120 more)
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
 130 P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP)
(120 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 130 P0AE82 (/IPI) P0AE82 (/IPI) P0AE82 (/IPI) P0AE82 (/IPI) P0AE82 (/IPI) P0AE82 (/IPI) P0AE82 (/IPI) P0AE82 (/IPI) P0AE82 (/IPI) P0AE82 (/IPI)
(120 more)
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
 7 Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
 130 P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP)
(120 more)
Signal transduction by protein phosphorylation GO:0023014
A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate.
 130 P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA)
(120 more)
Signal transduction by protein phosphorylation GO:0023014
A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate.
 130 P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP)
(120 more)
Cell adhesion involved in biofilm formation GO:0043708
The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.
 130 P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP) P0AE82 (/IMP)
(120 more)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
 130 P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA)
(120 more)
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
 7 Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS) Q9KNN8 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 130 P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA)
(120 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 130 P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA) P0AE82 (/IDA)
(120 more)