CATH Superfamily 1.10.287.130
Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 4: Ethylene receptor 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
10 | P39928 (/IPI) P39928 (/IPI) P49333 (/IPI) Q0WPQ2 (/IPI) Q38846 (/IPI) Q38846 (/IPI) Q41341 (/IPI) Q41342 (/IPI) Q9ZTP3 (/IPI) Q9ZTP3 (/IPI) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
7 | Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9P4U6 (/ISS) |
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
|
6 | Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) |
|
Ethylene binding GO:0051740
Interacting selectively and non-covalently with ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
|
6 | P49333 (/IDA) Q0WPQ2 (/IDA) Q38846 (/IDA) Q38846 (/IDA) Q9ZTP3 (/IDA) Q9ZTP3 (/IDA) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
4 | Q7XX84 (/IDA) Q7XX84 (/IDA) Q7XX84 (/IDA) Q7XX84 (/IDA) |
|
Protein histidine kinase activity GO:0004673
Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
|
3 | P49333 (/TAS) Q38846 (/TAS) Q38846 (/TAS) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
3 | Q0WPQ2 (/TAS) Q9ZTP3 (/TAS) Q9ZTP3 (/TAS) |
|
Protein histidine kinase activity GO:0004673
Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
|
2 | P39928 (/IDA) P39928 (/IDA) |
|
Osmosensor activity GO:0005034
Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.
|
2 | P39928 (/IDA) P39928 (/IDA) |
|
Histidine phosphotransfer kinase activity GO:0009927
Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.
|
2 | P39928 (/IDA) P39928 (/IDA) |
|
Histidine phosphotransfer kinase activity GO:0009927
Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.
|
2 | P39928 (/IMP) P39928 (/IMP) |
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
|
1 | Q9P4U6 (/IGI) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
1 | Q9P4U6 (/IGI) |
|
Protein histidine kinase activity GO:0004673
Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
|
1 | Q9P4U6 (/IGI) |
|
Protein histidine kinase activity GO:0004673
Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
|
1 | P49333 (/IMP) |
|
Protein histidine kinase activity GO:0004673
Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
|
1 | Q9P4U6 (/ISS) |
|
Ethylene receptor activity GO:0038199
Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity.
|
1 | P49333 (/IMP) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P49333 (/IPI) |
There are 38 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
|
6 | Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) Q9KS16 (/ISS) |
|
Negative regulation of ethylene-activated signaling pathway GO:0010105
Any process that stops or prevents ethylene (ethene) signal transduction.
|
6 | P49333 (/TAS) Q0WPQ2 (/TAS) Q38846 (/TAS) Q38846 (/TAS) Q9ZTP3 (/TAS) Q9ZTP3 (/TAS) |
|
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
|
5 | P49333 (/IMP) Q7XX84 (/IMP) Q7XX84 (/IMP) Q7XX84 (/IMP) Q7XX84 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | Q7XX84 (/IMP) Q7XX84 (/IMP) Q7XX84 (/IMP) Q7XX84 (/IMP) |
|
Regulation of starch metabolic process GO:2000904
Any process that modulates the frequency, rate or extent of starch metabolic process.
|
4 | Q7XX84 (/IMP) Q7XX84 (/IMP) Q7XX84 (/IMP) Q7XX84 (/IMP) |
|
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
|
2 | P39928 (/IGI) P39928 (/IGI) |
|
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
|
2 | P39928 (/IMP) P39928 (/IMP) |
|
Osmosensory signaling via phosphorelay pathway GO:0007234
A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
|
2 | P39928 (/IDA) P39928 (/IDA) |
|
Peptidyl-histidine phosphorylation GO:0018106
The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).
|
2 | P39928 (/IDA) P39928 (/IDA) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
2 | P39928 (/IDA) P39928 (/IDA) |
|
Osmosensory signaling MAPK cascade GO:0000161
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals, containing at least a Hog1/Sty1 family MAPK, a Pbs2/Wis1 family MAPKK and a Ssk2/Win1 family MAP3K.
|
1 | Q9P4U6 (/TAS) |
|
Response to molecule of bacterial origin GO:0002237
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
|
1 | P49333 (/IMP) |
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | Q9P4U6 (/IGI) |
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | Q9P4U6 (/ISS) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
1 | P49333 (/TAS) |
|
Osmosensory signaling via phosphorelay pathway GO:0007234
A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
|
1 | Q9P4U6 (/IGI) |
|
Osmosensory signaling via phosphorelay pathway GO:0007234
A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
|
1 | Q9P4U6 (/ISS) |
|
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | P49333 (/IMP) |
|
Response to insect GO:0009625
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.
|
1 | P49333 (/IMP) |
|
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
1 | P49333 (/IEP) |
|
Cytokinin metabolic process GO:0009690
The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.
|
1 | P49333 (/IMP) |
|
Detection of ethylene stimulus GO:0009727
The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.
|
1 | P49333 (/IMP) |
|
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
|
1 | P49333 (/IMP) |
|
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
|
1 | P49333 (/IMP) |
|
Response to gibberellin GO:0009739
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
|
1 | P49333 (/IMP) |
|
Phloem or xylem histogenesis GO:0010087
The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.
|
1 | P49333 (/IMP) |
|
Regulation of stomatal movement GO:0010119
Any process that modulates the frequency, rate or extent of stomatal movement.
|
1 | P49333 (/IMP) |
|
Sugar mediated signaling pathway GO:0010182
The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.
|
1 | P49333 (/TAS) |
|
CAMP-mediated signaling GO:0019933
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.
|
1 | Q86CZ2 (/IMP) |
|
Culmination involved in sorocarp development GO:0031154
The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.
|
1 | Q86CZ2 (/IMP) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
1 | P49333 (/IMP) |
|
Hydrogen peroxide biosynthetic process GO:0050665
The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
|
1 | P49333 (/IMP) |
|
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
|
1 | P49333 (/IMP) |
|
Defense response by callose deposition in cell wall GO:0052544
Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
|
1 | P49333 (/IMP) |
|
Conidiophore development GO:0070787
The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
|
1 | A4D9V5 (/IMP) |
|
Positive regulation of conidiophore development GO:0070795
Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
|
1 | A4D9V5 (/IMP) |
|
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
|
1 | P49333 (/IEP) |
|
Regulation of seedling development GO:1900140
Any process that modulates the frequency, rate or extent of seedling development.
|
1 | P49333 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
6 | P49333 (/IDA) Q0WPQ2 (/IDA) Q38846 (/IDA) Q38846 (/IDA) Q9ZTP3 (/IDA) Q9ZTP3 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P39928 (/IDA) P39928 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | P39928 (/IDA) P39928 (/IDA) |
|
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
|
2 | P39928 (/HDA) P39928 (/HDA) |
|
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | Q86CZ2 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9P4U6 (/IGI) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9P4U6 (/ISS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9P4U6 (/NAS) |