The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DnaJ domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Molecular chaperone DnaJ

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein disulfide isomerase activity GO:0003756
Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P08622 (/IPI) P08622 (/IPI) P08622 (/IPI) P08622 (/IPI) P08622 (/IPI)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
5 P08622 (/IMP) P08622 (/IMP) P08622 (/IMP) P08622 (/IMP) P08622 (/IMP)
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Sigma factor antagonist activity GO:0016989
The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
5 P08622 (/IPI) P08622 (/IPI) P08622 (/IPI) P08622 (/IPI) P08622 (/IPI)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
8 O34242 (/ISS) O34242 (/ISS) O34242 (/ISS) O34242 (/ISS) O34242 (/ISS) O34242 (/ISS) O34242 (/ISS) O34242 (/ISS)
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
5 P08622 (/IMP) P08622 (/IMP) P08622 (/IMP) P08622 (/IMP) P08622 (/IMP)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
5 P08622 (/IEP) P08622 (/IEP) P08622 (/IEP) P08622 (/IEP) P08622 (/IEP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
5 P08622 (/IMP) P08622 (/IMP) P08622 (/IMP) P08622 (/IMP) P08622 (/IMP)
Viral process GO:0016032
A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Viral process GO:0016032
A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.
5 P08622 (/IMP) P08622 (/IMP) P08622 (/IMP) P08622 (/IMP) P08622 (/IMP)
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Chaperone cofactor-dependent protein refolding GO:0051085
The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
5 P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA) P08622 (/IDA)