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CATH Superfamily 1.10.286.70

Get5 dimerization domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Get5 dimerization domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Get5 dimerization domain

Structural domains comprising this superfamily share the structure of the carboxyl dimerization domain of Get5, which enables either homodimerization or complex formation with Get4. Tail-anchored transmembrane proteins are targeted to membranes post-translationally. This is mediated by the obligate Get4-Get5 complex, which catalyzes the transfer of tail-anchored proteins destined to the endoplasmic reticulum from Sgt2 to the cytosolic targeting factor Get3 PMID:22262836.

GO Diversity

Unique GO annotations
8 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
459 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 6
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 3
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 2
Function
Unique EC:
Unique GO: 8
Taxonomy
Unique Species: 459