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CATH Superfamily 1.10.286.10

GTP cyclohydrolase I, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: GTP cyclohydrolase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTP cyclohydrolase I activity GO:0003934
Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
 189 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(179 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
 189 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(179 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
 189 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(179 more)
GTP cyclohydrolase I activity GO:0003934
Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
 9 Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Queuosine biosynthetic process GO:0008616
The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
 189 P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP) P0A6T5 (/IMP)
(179 more)
Folic acid-containing compound metabolic process GO:0006760
The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
 9 Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS) Q9KLX5 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 189 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(179 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 189 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(179 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
 189 P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA) P0A6T5 (/IDA)
(179 more)