The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (N-terminal domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Phenylalanine ammonia-lyase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 F4JW69 (/IPI) P35510 (/IPI) P35510 (/IPI) P45724 (/IPI)
Phenylalanine ammonia-lyase activity GO:0045548
Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.
3 P35510 (/IDA) P35510 (/IDA) Q8VXG7 (/IDA)
Intramolecular transferase activity, transferring amino groups GO:0016869
Catalysis of the transfer of an amino group from one position to another within a single molecule.
2 Q68G84 (/IDA) Q6GZ04 (/IDA)
Amino acid binding GO:0016597
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
1 P24481 (/TAS)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
1 Q6UD65 (/TAS)
Phenylalanine ammonia-lyase activity GO:0045548
Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.
1 F4JW69 (/ISS)
Phenylalanine ammonia-lyase activity GO:0045548
Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.
1 P45724 (/TAS)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
3 P35510 (/IEP) P35510 (/IEP) P45724 (/IEP)
Response to karrikin GO:0080167
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants).
3 P35510 (/IEP) P35510 (/IEP) P45724 (/IEP)
L-phenylalanine metabolic process GO:0006558
The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.
2 Q68G84 (/IDA) Q6GZ04 (/IDA)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
2 P35510 (/IMP) P35510 (/IMP)
Phenylpropanoid biosynthetic process GO:0009699
The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid.
2 P45724 (/TAS) Q8VXG7 (/TAS)
Drought recovery GO:0009819
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.
2 P35510 (/IMP) P35510 (/IMP)
Alkaloid biosynthetic process GO:0009821
The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).
2 Q68G84 (/TAS) Q6GZ04 (/TAS)
Response to UV-B GO:0010224
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
2 P35510 (/IMP) P35510 (/IMP)
Paclitaxel biosynthetic process GO:0042617
The chemical reactions and pathways resulting in the formation of paclitaxel, an alkaloid compound used as an anticancer treatment.
2 Q68G84 (/TAS) Q6GZ04 (/TAS)
Salicylic acid catabolic process GO:0046244
The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.
2 P35510 (/IMP) P35510 (/IMP)
Lignin catabolic process GO:0046274
The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units.
2 P35510 (/IMP) P35510 (/IMP)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
2 Q68G84 (/IDA) Q6GZ04 (/IDA)
Response to gibberellin GO:0009739
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
1 Q8VXG7 (/IDA)
Protein arginylation GO:0016598
The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway.
1 Q8VXG7 (/IC)
Protein arginylation GO:0016598
The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway.
1 Q8VXG7 (/IDA)
Response to cycloheximide GO:0046898
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.
1 Q8VXG7 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
5 P24481 (/TAS) P26600 (/TAS) P35511 (/TAS) P45728 (/TAS) P45729 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P45724 (/IDA)