The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 21: Mitochondrial Rho GTPase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 A0A0G2K777 (/IPI) A1L1L6 (/IPI) Q8IXI1 (/IPI) Q8IXI2 (/IPI)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular homeostasis GO:0019725
Any process involved in the maintenance of an internal steady state at the level of the cell.
10 Q2HJF8 (/ISS) Q32LU1 (/ISS) Q5E9M9 (/ISS) Q5ZM73 (/ISS) Q5ZM83 (/ISS) Q6DIS1 (/ISS) Q6NVC5 (/ISS) Q7TSA0 (/ISS) Q8BG51 (/ISS) Q8JZN7 (/ISS)
Mitochondrion transport along microtubule GO:0047497
The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
10 Q2HJF8 (/ISS) Q32LU1 (/ISS) Q5E9M9 (/ISS) Q5ZM73 (/ISS) Q5ZM83 (/ISS) Q6DIS1 (/ISS) Q6NVC5 (/ISS) Q7TSA0 (/ISS) Q8BG51 (/ISS) Q8JZN7 (/ISS)
Mitochondrial outer membrane permeabilization GO:0097345
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.
10 Q2HJF8 (/ISS) Q32LU1 (/ISS) Q5E9M9 (/ISS) Q5ZM73 (/ISS) Q5ZM83 (/ISS) Q6DIS1 (/ISS) Q6NVC5 (/ISS) Q7TSA0 (/ISS) Q8BG51 (/ISS) Q8JZN7 (/ISS)
Cellular homeostasis GO:0019725
Any process involved in the maintenance of an internal steady state at the level of the cell.
2 Q8IXI1 (/IMP) Q8IXI2 (/IMP)
Cellular homeostasis GO:0019725
Any process involved in the maintenance of an internal steady state at the level of the cell.
2 Q8BG51 (/ISO) Q8JZN7 (/ISO)
Establishment of mitochondrion localization by microtubule attachment GO:0034640
The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.
2 A0A0G2K777 (/IMP) A1L1L6 (/IMP)
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
2 A0A0G2K777 (/IMP) A1L1L6 (/IMP)
Mitochondrion transport along microtubule GO:0047497
The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
2 Q8IXI1 (/IMP) Q8IXI2 (/IMP)
Mitochondrion transport along microtubule GO:0047497
The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
2 Q8BG51 (/ISO) Q8JZN7 (/ISO)
Regulation of small GTPase mediated signal transduction GO:0051056
Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.
2 Q8IXI1 (/TAS) Q8IXI2 (/TAS)
Mitochondrial outer membrane permeabilization GO:0097345
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.
2 Q8IXI1 (/IMP) Q8IXI2 (/IMP)
Mitochondrial outer membrane permeabilization GO:0097345
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.
2 Q8BG51 (/ISO) Q8JZN7 (/ISO)
Regulation of organelle transport along microtubule GO:1902513
Any process that modulates the frequency, rate or extent of organelle transport along microtubule.
2 A0A0G2K777 (/IMP) A1L1L6 (/IMP)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
1 Q8IXI2 (/TAS)
Establishment of mitochondrion localization by microtubule attachment GO:0034640
The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.
1 Q8BG51 (/ISO)
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
1 Q8BG51 (/ISO)
Regulation of organelle transport along microtubule GO:1902513
Any process that modulates the frequency, rate or extent of organelle transport along microtubule.
1 Q8BG51 (/ISO)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
10 Q2HJF8 (/ISS) Q32LU1 (/ISS) Q5E9M9 (/ISS) Q5ZM73 (/ISS) Q5ZM83 (/ISS) Q6DIS1 (/ISS) Q6NVC5 (/ISS) Q7TSA0 (/ISS) Q8BG51 (/ISS) Q8JZN7 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 A0A0R4IGX0 (/IDA) A0A0R4IVN5 (/IDA) A0A286Y9M7 (/IDA) B3DI88 (/IDA) Q32LU1 (/IDA) Q6NVC5 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q8BG51 (/HDA) Q8JZN7 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q8IXI1 (/TAS) Q8IXI2 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q8IXI1 (/TAS) Q8IXI2 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 Q8IXI1 (/HDA) Q8IXI2 (/HDA)
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q8IXI1 (/IDA) Q8IXI2 (/IDA)
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q8BG51 (/ISO) Q8JZN7 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8IXI2 (/NAS)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
1 Q8IXI2 (/TAS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 Q8JZN7 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8IXI1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8JZN7 (/ISO)