The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 156: Actinin alpha 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of fast-twitch skeletal muscle fiber contraction GO:0031448
Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction.
1 Q4VAM3 (/ISS)
Positive regulation of skeletal muscle tissue growth GO:0048633
Any process that activates, maintains or increases the rate of skeletal muscle growth.
1 Q4VAM3 (/ISS)
Positive regulation of skeletal muscle fiber development GO:0048743
Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
1 Q4VAM3 (/ISS)
Regulation of muscle system process GO:0090257
Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system.
1 Q4VAM3 (/ISS)
Negative regulation of oxidative phosphorylation GO:0090324
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
1 Q4VAM3 (/ISS)
Negative regulation of relaxation of muscle GO:1901078
Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle.
1 Q4VAM3 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 F5GXS2 (/IDA) F5GXS2 (/IDA) H7C144 (/IDA) H7C144 (/IDA)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
4 F5GXS2 (/IDA) F5GXS2 (/IDA) H7C144 (/IDA) H7C144 (/IDA)