The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450-Terp, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Citrate synthase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Citrate synthase (unknown stereospecificity). [EC: 2.3.3.16]
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
  • This entry has been included to accommodate those citrate synthases for which the stereospecificity with respect to C(2) of oxaloacetate has not been established (cf. EC 2.3.3.1 and EC 2.3.3.3).
1615 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2
(1605 more...)
2-methylcitrate synthase. [EC: 2.3.3.5]
Propanoyl-CoA + H(2)O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3- tricarboxylate + CoA.
  • The enzyme acts on acetyl-CoA, propanoyl-CoA, butanoyl-CoA and pentanoyl-CoA.
  • The relative rate of condensation of acetyl-CoA and oxaloacetate is 140% of that of propanoyl-CoA and oxaloacetate, but the enzyme is distinct from EC 2.3.3.1.
  • Oxaloacetate cannot be replaced by glyoxylate, pyruvate or 2-oxoglutarate.
  • Formerly EC 4.1.3.31.
1535 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2 A0A045IMZ2
(1525 more...)