The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Saposin-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Canopy 2 homolog (Zebrafish)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q9Y2B0 (/IPI) Q9Y2B0 (/IPI) Q9Y2B0 (/IPI) Q9Y2B0 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
4 Q9Y2B0 (/ISS) Q9Y2B0 (/ISS) Q9Y2B0 (/ISS) Q9Y2B0 (/ISS)
Regulation of low-density lipoprotein particle clearance GO:0010988
Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
4 Q9Y2B0 (/ISS) Q9Y2B0 (/ISS) Q9Y2B0 (/ISS) Q9Y2B0 (/ISS)
Positive regulation of low-density lipoprotein particle receptor biosynthetic process GO:0045716
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors.
4 Q9Y2B0 (/ISS) Q9Y2B0 (/ISS) Q9Y2B0 (/ISS) Q9Y2B0 (/ISS)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q9QXT0 (/IMP)
Regulation of low-density lipoprotein particle clearance GO:0010988
Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
1 Q9QXT0 (/IMP)
Positive regulation of low-density lipoprotein particle receptor biosynthetic process GO:0045716
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors.
1 Q9QXT0 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.