The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transcription Factor, Ets-1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 38: Putative sam and sh3 domain-containing protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 O94885 (/IDA)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 P59808 (/ISO)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 O94885 (/IDA)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 P59808 (/ISO)
Mitogen-activated protein kinase kinase kinase binding GO:0031435
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase.
1 O94885 (/IDA)
Mitogen-activated protein kinase kinase kinase binding GO:0031435
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase.
1 P59808 (/ISO)
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
1 O94885 (/IDA)
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
1 P59808 (/ISO)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
1 O94885 (/IDA)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
1 P59808 (/ISO)
Positive regulation of endothelial cell migration GO:0010595
Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
1 O94885 (/IDA)
Positive regulation of endothelial cell migration GO:0010595
Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
1 P59808 (/ISO)
Positive regulation of lipopolysaccharide-mediated signaling pathway GO:0031666
Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
1 O94885 (/IMP)
Positive regulation of lipopolysaccharide-mediated signaling pathway GO:0031666
Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
1 P59808 (/ISO)
Positive regulation of JUN kinase activity GO:0043507
Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
1 O94885 (/IMP)
Positive regulation of JUN kinase activity GO:0043507
Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
1 P59808 (/ISO)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
1 O94885 (/IMP)
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
1 P59808 (/ISO)
Regulation of protein K63-linked ubiquitination GO:1900044
Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination.
1 O94885 (/IDA)
Regulation of protein K63-linked ubiquitination GO:1900044
Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination.
1 P59808 (/ISO)
Positive regulation of p38MAPK cascade GO:1900745
Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.
1 O94885 (/IMP)
Positive regulation of p38MAPK cascade GO:1900745
Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.
1 P59808 (/ISO)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
1 O94885 (/IMP)
Positive regulation of NIK/NF-kappaB signaling GO:1901224
Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
1 P59808 (/ISO)
Regulation of protein autoubiquitination GO:1902498
Any process that modulates the frequency, rate or extent of protein autoubiquitination.
1 O94885 (/IDA)
Regulation of protein autoubiquitination GO:1902498
Any process that modulates the frequency, rate or extent of protein autoubiquitination.
1 P59808 (/ISO)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P59808 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 O94885 (/IMP)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 P59808 (/ISO)