The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Tetraspanin
".
FunFam 5: Tetraspanin
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
6 | O35566 (/ISS) P61170 (/ISS) P61170 (/ISS) P61171 (/ISS) P61171 (/ISS) Q3ZBH3 (/ISS) |
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
5 | P48509 (/IPI) P48509 (/IPI) P48509 (/IPI) P48509 (/IPI) Q9QZA6 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | O35566 (/IPI) P48509 (/IPI) P48509 (/IPI) P48509 (/IPI) P48509 (/IPI) |
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
4 | P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) |
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
1 | O35566 (/ISO) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
4 | P48509 (/NAS) P48509 (/NAS) P48509 (/NAS) P48509 (/NAS) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
4 | P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
4 | P48509 (/IMP) P48509 (/IMP) P48509 (/IMP) P48509 (/IMP) |
|
Hemidesmosome assembly GO:0031581
Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.
|
4 | P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) |
|
Wound healing, spreading of cells GO:0044319
The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface.
|
4 | P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) |
|
Wound healing, spreading of cells GO:0044319
The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface.
|
4 | P48509 (/IMP) P48509 (/IMP) P48509 (/IMP) P48509 (/IMP) |
|
Positive regulation of endocytosis GO:0045807
Any process that activates or increases the frequency, rate or extent of endocytosis.
|
4 | P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) |
|
Positive regulation of endocytosis GO:0045807
Any process that activates or increases the frequency, rate or extent of endocytosis.
|
4 | P48509 (/IMP) P48509 (/IMP) P48509 (/IMP) P48509 (/IMP) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | O35566 (/IMP) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
1 | O35566 (/ISO) |
|
T cell proliferation GO:0042098
The expansion of a T cell population by cell division. Follows T cell activation.
|
1 | O35566 (/IMP) |
|
Wound healing, spreading of cells GO:0044319
The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface.
|
1 | O35566 (/ISO) |
|
Positive regulation of endocytosis GO:0045807
Any process that activates or increases the frequency, rate or extent of endocytosis.
|
1 | O35566 (/ISO) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
4 | P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | P48509 (/NAS) P48509 (/NAS) P48509 (/NAS) P48509 (/NAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
4 | P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
4 | P48509 (/HDA) P48509 (/HDA) P48509 (/HDA) P48509 (/HDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
4 | P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) P48509 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
4 | P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) P48509 (/TAS) |
|
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
1 | O35566 (/ISO) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | O35566 (/ISO) |