The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Neutral endopeptidase , domain2

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: endothelin-converting enzyme 2 isoform X1

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Endothelin-converting enzyme 1. [EC:]
Hydrolysis of the 21-Trp-|-Val-22 bond in big endothelin to form endothelin 1.
  • Phosphoramidon-sensitive.
  • Belongs to peptidase family M13.
14 A0A024RAF7 A0A024RAF7 B2RQR8 F1N476 P0DPD6 P0DPD8 P0DPD9 P0DPE2 P42891 P42892
(4 more...)