The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 377: DNA-binding E3 ubiquitin-protein ligase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
5 P53127 (/IDA) P53127 (/IDA) P53127 (/IDA) P53127 (/IDA) P53127 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histone ubiquitination GO:0016574
The modification of histones by addition of ubiquitin groups.
5 P53127 (/IDA) P53127 (/IDA) P53127 (/IDA) P53127 (/IDA) P53127 (/IDA)
Histone catabolic process GO:0036205
The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.
5 P53127 (/IMP) P53127 (/IMP) P53127 (/IMP) P53127 (/IMP) P53127 (/IMP)
Regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0043619
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 P53127 (/IDA) P53127 (/IDA) P53127 (/IDA) P53127 (/IDA) P53127 (/IDA)
Regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0043619
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 P53127 (/IMP) P53127 (/IMP) P53127 (/IMP) P53127 (/IMP) P53127 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 P53127 (/HDA) P53127 (/HDA) P53127 (/HDA) P53127 (/HDA) P53127 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P53127 (/HDA) P53127 (/HDA) P53127 (/HDA) P53127 (/HDA) P53127 (/HDA)
Snt2C complex GO:0070211
A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p.
5 P53127 (/HDA) P53127 (/HDA) P53127 (/HDA) P53127 (/HDA) P53127 (/HDA)