The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 353: Transcription factor WER

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
7 P27900 (/ISS) P27900 (/ISS) Q96276 (/ISS) Q96276 (/ISS) Q9SEI0 (/ISS) Q9SEI0 (/ISS) Q9SEI0 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P27900 (/IPI) P27900 (/IPI) Q96276 (/IPI) Q96276 (/IPI) Q9SEI0 (/IPI) Q9SEI0 (/IPI) Q9SEI0 (/IPI)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 Q9SEI0 (/IPI) Q9SEI0 (/IPI) Q9SEI0 (/IPI)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 P27900 (/IDA) P27900 (/IDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 P27900 (/TAS) P27900 (/TAS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 Q6GVK7 (/ISA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
1 Q6GVK7 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q6GVK7 (/IDA)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Trichome differentiation GO:0010026
The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana.
4 P27900 (/IMP) P27900 (/IMP) Q96276 (/IMP) Q96276 (/IMP)
Cell fate commitment GO:0045165
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
3 Q9SEI0 (/IMP) Q9SEI0 (/IMP) Q9SEI0 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
3 Q9SEI0 (/IMP) Q9SEI0 (/IMP) Q9SEI0 (/IMP)
Root hair cell differentiation GO:0048765
The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.
3 Q9SEI0 (/IMP) Q9SEI0 (/IMP) Q9SEI0 (/IMP)
Cell fate specification GO:0001708
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
2 P27900 (/IMP) P27900 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 Q96276 (/TAS) Q96276 (/TAS)
Gibberellic acid mediated signaling pathway GO:0009740
A series of molecular signals mediated by the detection of gibberellic acid.
2 P27900 (/TAS) P27900 (/TAS)
Jasmonic acid mediated signaling pathway GO:0009867
A series of molecular signals mediated by jasmonic acid.
2 P27900 (/IMP) P27900 (/IMP)
Root epidermal cell differentiation GO:0010053
The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast.
2 Q96276 (/IMP) Q96276 (/IMP)
Trichome branching GO:0010091
Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.
2 Q96276 (/IMP) Q96276 (/IMP)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
2 P27900 (/IMP) P27900 (/IMP)
Trichome patterning GO:0048629
The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes.
2 P27900 (/IMP) P27900 (/IMP)
Seed trichome initiation GO:0090377
The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis.
2 Q6GVK7 (/IEP) Q70SX1 (/IEP)
Seed trichome elongation GO:0090378
The process in which a seed trichome irreversibly increases in size in one
2 Q6GVK7 (/IEP) Q70SX1 (/IEP)
Regulation of trichome morphogenesis GO:2000039
Any process that modulates the frequency, rate or extent of trichome morphogenesis.
2 P27900 (/IMP) P27900 (/IMP)
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
1 Q6GVK7 (/TAS)
Cell fate commitment GO:0045165
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
1 Q6GVK7 (/ISA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q6GVK7 (/ISA)
Root hair cell differentiation GO:0048765
The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.
1 Q6GVK7 (/ISA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q96276 (/IDA) Q96276 (/IDA) Q9SEI0 (/IDA) Q9SEI0 (/IDA) Q9SEI0 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P27900 (/TAS) P27900 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q6GVK7 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q6GVK7 (/ISA)