The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 14: SWI/SNF complex subunit SMARCC2 isoform C
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
17 |
A0A0B4JDA0 (/IPI)
D4A510 (/IPI)
G5EF87 (/IPI)
P32591 (/IPI)
P43609 (/IPI)
P43609 (/IPI)
P97496 (/IPI)
Q6PDG5 (/IPI)
Q7KPY3 (/IPI)
Q8MSY3 (/IPI)
(7 more) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
5 | Q8TAQ2 (/ISA) Q8TAQ2 (/ISA) Q8TAQ2 (/ISA) Q8TAQ2 (/ISA) Q92922 (/ISA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
5 | Q8TAQ2 (/NAS) Q8TAQ2 (/NAS) Q8TAQ2 (/NAS) Q8TAQ2 (/NAS) Q92922 (/NAS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
3 | P32591 (/IDA) P43609 (/IDA) P43609 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | O13788 (/ISM) O14470 (/ISM) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
2 | P97496 (/IDA) Q6PDG5 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | G5EF87 (/IPI) Q7KPY3 (/IPI) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | P32591 (/IMP) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | P32591 (/IPI) |
|
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | Q92922 (/IPI) |
|
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | P97496 (/ISO) |
There are 58 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
9 | A0A0B4JDA0 (/IDA) Q7KPY3 (/IDA) Q8MSY3 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q92922 (/IDA) Q9VF03 (/IDA) |
|
Nucleosome disassembly GO:0006337
The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
7 | P43609 (/IDA) P43609 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q92922 (/IDA) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
5 | Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q92922 (/IDA) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
5 | Q8TAQ2 (/NAS) Q8TAQ2 (/NAS) Q8TAQ2 (/NAS) Q8TAQ2 (/NAS) Q92922 (/NAS) |
|
ATP-dependent chromatin remodeling GO:0043044
Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors.
|
5 | Q8TAQ2 (/HDA) Q8TAQ2 (/HDA) Q8TAQ2 (/HDA) Q8TAQ2 (/HDA) Q92922 (/HDA) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
4 | A0A0B4JDA0 (/IMP) Q7KPY3 (/IMP) Q8MSY3 (/IMP) Q9VF03 (/IMP) |
|
Negative regulation of neuroblast proliferation GO:0007406
Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.
|
4 | A0A0B4JDA0 (/IGI) Q7KPY3 (/IGI) Q8MSY3 (/IGI) Q9VF03 (/IGI) |
|
Imaginal disc-derived wing vein specification GO:0007474
The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.
|
4 | A0A0B4JDA0 (/IMP) Q7KPY3 (/IMP) Q8MSY3 (/IMP) Q9VF03 (/IMP) |
|
Imaginal disc-derived leg morphogenesis GO:0007480
The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.
|
4 | A0A0B4JDA0 (/IGI) Q7KPY3 (/IGI) Q8MSY3 (/IGI) Q9VF03 (/IGI) |
|
Imaginal disc-derived wing vein morphogenesis GO:0008586
The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.
|
4 | A0A0B4JDA0 (/IMP) Q7KPY3 (/IMP) Q8MSY3 (/IMP) Q9VF03 (/IMP) |
|
Imaginal disc-derived wing margin morphogenesis GO:0008587
The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade.
|
4 | A0A0B4JDA0 (/IMP) Q7KPY3 (/IMP) Q8MSY3 (/IMP) Q9VF03 (/IMP) |
|
ATP-dependent chromatin remodeling GO:0043044
Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors.
|
4 | A0A0B4JDA0 (/ISS) Q7KPY3 (/ISS) Q8MSY3 (/ISS) Q9VF03 (/ISS) |
|
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
|
4 | A0A0B4JDA0 (/IGI) Q7KPY3 (/IGI) Q8MSY3 (/IGI) Q9VF03 (/IGI) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | A0A0B4JDA0 (/ISS) Q7KPY3 (/ISS) Q8MSY3 (/ISS) Q9VF03 (/ISS) |
|
Negative regulation of G1/S transition of mitotic cell cycle GO:2000134
Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
|
4 | A0A0B4JDA0 (/IGI) Q7KPY3 (/IGI) Q8MSY3 (/IGI) Q9VF03 (/IGI) |
|
Reproduction GO:0000003
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
|
3 | G5EF87 (/IGI) H8ESF3 (/IGI) H8ESF4 (/IGI) |
|
Reproduction GO:0000003
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
|
3 | G5EF87 (/IMP) H8ESF3 (/IMP) H8ESF4 (/IMP) |
|
Morphogenesis of an epithelium GO:0002009
The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
|
3 | G5EF87 (/IMP) H8ESF3 (/IMP) H8ESF4 (/IMP) |
|
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
|
3 | G5EF87 (/IGI) H8ESF3 (/IGI) H8ESF4 (/IGI) |
|
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
|
3 | G5EF87 (/IMP) H8ESF3 (/IMP) H8ESF4 (/IMP) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
3 | O13788 (/ISO) P97496 (/ISO) Q6PDG5 (/ISO) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
3 | G5EF87 (/IGI) H8ESF3 (/IGI) H8ESF4 (/IGI) |
|
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
3 | G5EF87 (/IMP) H8ESF3 (/IMP) H8ESF4 (/IMP) |
|
Gonad morphogenesis GO:0035262
The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.
|
3 | G5EF87 (/IMP) H8ESF3 (/IMP) H8ESF4 (/IMP) |
|
Positive regulation of growth rate GO:0040010
Any process that increases the rate of growth of all or part of an organism.
|
3 | G5EF87 (/IMP) H8ESF3 (/IMP) H8ESF4 (/IMP) |
|
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
|
3 | G5EF87 (/IGI) H8ESF3 (/IGI) H8ESF4 (/IGI) |
|
Negative regulation of vulval development GO:0040027
Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
|
3 | G5EF87 (/IMP) H8ESF3 (/IMP) H8ESF4 (/IMP) |
|
Hermaphrodite genitalia development GO:0040035
The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures.
|
3 | G5EF87 (/IMP) H8ESF3 (/IMP) H8ESF4 (/IMP) |
|
ATP-dependent chromatin remodeling GO:0043044
Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors.
|
3 | P32591 (/IDA) P43609 (/IDA) P43609 (/IDA) |
|
Regulation of oviposition GO:0046662
Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.
|
3 | G5EF87 (/IMP) H8ESF3 (/IMP) H8ESF4 (/IMP) |
|
Heart morphogenesis GO:0003007
The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
2 | F1Q9K1 (/IMP) Q7ZUU5 (/IMP) |
|
Double-strand break repair via nonhomologous end joining GO:0006303
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
|
2 | P43609 (/IDA) P43609 (/IDA) |
|
Double-strand break repair via nonhomologous end joining GO:0006303
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
|
2 | P43609 (/IMP) P43609 (/IMP) |
|
Nucleosome disassembly GO:0006337
The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
2 | P97496 (/ISO) Q6PDG5 (/ISO) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
2 | Q550R6 (/ISS) Q9XI07 (/ISS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P43609 (/IMP) P43609 (/IMP) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | O13788 (/IPI) O14470 (/IPI) |
|
Transcription elongation from RNA polymerase II promoter GO:0006368
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
|
2 | P43609 (/IDA) P43609 (/IDA) |
|
Prostate gland development GO:0030850
The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
|
2 | A0A0G2K9D6 (/IEP) D3ZJU5 (/IEP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P97496 (/ISO) Q6PDG5 (/ISO) |
|
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
|
2 | F1Q9K1 (/IMP) Q7ZUU5 (/IMP) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q6PDG5 (/IGI) |
|
Carbon catabolite activation of transcription from RNA polymerase II promoter GO:0000436
Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P32591 (/IMP) |
|
Sucrose catabolic process GO:0005987
The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside.
|
1 | P32591 (/IMP) |
|
DNA packaging GO:0006323
Any process in which DNA and associated proteins are formed into a compact, orderly structure.
|
1 | P97496 (/TAS) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | O14470 (/NAS) |
|
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
1 | P97496 (/IDA) |
|
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
1 | P97496 (/IMP) |
|
Regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment GO:0021882
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
|
1 | Q6PDG5 (/IMP) |
|
Positive regulation of mating type switching GO:0031496
Any process that activates or increases the frequency, rate or extent of mating type switching.
|
1 | P32591 (/IMP) |
|
Negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435
Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | P97496 (/IDA) |
|
Negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435
Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | P97496 (/IMP) |
|
Cellular alcohol catabolic process GO:0044109
The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, occurring at the level of the individual cell.
|
1 | P32591 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | D4A510 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q6PDG5 (/ISO) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P97496 (/IGI) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P32591 (/IMP) |
There are 26 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
12 |
A0A024RB22 (/IDA)
A0A024RB22 (/IDA)
A0A024RB22 (/IDA)
A0A024RB22 (/IDA)
F8VXC8 (/IDA)
F8VXC8 (/IDA)
F8VXC8 (/IDA)
Q8TAQ2 (/IDA)
Q8TAQ2 (/IDA)
Q8TAQ2 (/IDA)
(2 more) |
|
SWI/SNF complex GO:0016514
A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof.
|
10 | O13788 (/IDA) O14470 (/IDA) P32591 (/IDA) P97496 (/IDA) Q6PDG5 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q8TAQ2 (/IDA) Q92922 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
9 | A0A0B4JDA0 (/IDA) F1Q9K1 (/IDA) P32591 (/IDA) P97496 (/IDA) Q7KPY3 (/IDA) Q7ZUU5 (/IDA) Q8MSY3 (/IDA) Q92922 (/IDA) Q9VF03 (/IDA) |
|
RSC-type complex GO:0016586
A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining
|
8 | A0A0B4JDA0 (/IDA) O13788 (/IDA) O14470 (/IDA) P43609 (/IDA) P43609 (/IDA) Q7KPY3 (/IDA) Q8MSY3 (/IDA) Q9VF03 (/IDA) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
5 | Q8TAQ2 (/HDA) Q8TAQ2 (/HDA) Q8TAQ2 (/HDA) Q8TAQ2 (/HDA) Q92922 (/HDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
5 | Q8TAQ2 (/TAS) Q8TAQ2 (/TAS) Q8TAQ2 (/TAS) Q8TAQ2 (/TAS) Q92922 (/TAS) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
5 | Q8TAQ2 (/HDA) Q8TAQ2 (/HDA) Q8TAQ2 (/HDA) Q8TAQ2 (/HDA) Q92922 (/HDA) |
|
NpBAF complex GO:0071564
A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.
|
5 | Q8TAQ2 (/ISS) Q8TAQ2 (/ISS) Q8TAQ2 (/ISS) Q8TAQ2 (/ISS) Q92922 (/ISS) |
|
NBAF complex GO:0071565
A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
|
5 | Q8TAQ2 (/ISS) Q8TAQ2 (/ISS) Q8TAQ2 (/ISS) Q8TAQ2 (/ISS) Q92922 (/ISS) |
|
Brahma complex GO:0035060
A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof.
|
4 | A0A0B4JDA0 (/IDA) Q7KPY3 (/IDA) Q8MSY3 (/IDA) Q9VF03 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | O13788 (/HDA) P43609 (/HDA) P43609 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | F1Q9K1 (/IDA) Q7ZUU5 (/IDA) Q92922 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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2 | P97496 (/ISO) Q6PDG5 (/ISO) |
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SWI/SNF complex GO:0016514
A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof.
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2 | P97496 (/ISO) Q6PDG5 (/ISO) |
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SWI/SNF complex GO:0016514
A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof.
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2 | Q550R6 (/ISS) Q9XI07 (/ISS) |
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NpBAF complex GO:0071564
A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.
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2 | P97496 (/IDA) Q6PDG5 (/IDA) |
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NBAF complex GO:0071565
A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
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2 | P97496 (/IDA) Q6PDG5 (/IDA) |
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XY body GO:0001741
A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
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1 | P97496 (/IDA) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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1 | P97496 (/ISO) |
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Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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1 | O14470 (/HDA) |
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Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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1 | P97496 (/ISO) |
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Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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1 | P97496 (/ISS) |
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Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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1 | O13788 (/HDA) |
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Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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1 | P32591 (/IDA) |
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SWI/SNF complex GO:0016514
A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof.
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1 | P32591 (/IMP) |
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SWI/SNF complex GO:0016514
A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof.
|
1 | P97496 (/TAS) |