The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 137: MYB DNA binding protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
7 | Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
7 | Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | Q02457 (/IPI) Q02457 (/IPI) Q02457 (/IPI) Q02457 (/IPI) Q02457 (/IPI) Q02457 (/IPI) Q02457 (/IPI) |
|
Telomeric DNA binding GO:0042162
Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.
|
7 | Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) |
|
Chromatin insulator sequence binding GO:0043035
Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.
|
7 | Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) |
|
Double-stranded telomeric DNA binding GO:0003691
Interacting selectively and non-covalently with double-stranded telomere-associated DNA.
|
1 | Q6E434 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
1 | Q5AHJ5 (/ISA) |
|
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
1 | Q5AHJ5 (/IMP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q5AHJ5 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
SnoRNA transcription by RNA polymerase II GO:0001015
The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
|
7 | Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) |
|
SnoRNA transcription by RNA polymerase II GO:0001015
The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
|
7 | Q02457 (/IMP) Q02457 (/IMP) Q02457 (/IMP) Q02457 (/IMP) Q02457 (/IMP) Q02457 (/IMP) Q02457 (/IMP) |
|
Telomere maintenance via telomere lengthening GO:0010833
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA.
|
7 | Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) |
|
Negative regulation of chromatin silencing GO:0031936
Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing.
|
7 | Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) |
|
Negative regulation of telomere maintenance via telomerase GO:0032211
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
7 | Q02457 (/IGI) Q02457 (/IGI) Q02457 (/IGI) Q02457 (/IGI) Q02457 (/IGI) Q02457 (/IGI) Q02457 (/IGI) |
|
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
|
1 | Q6E434 (/IMP) |
|
RRNA transcription GO:0009303
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.
|
1 | Q5AHJ5 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q5AHJ5 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
|
8 | Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q02457 (/IDA) Q6E434 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | Q02457 (/HDA) Q02457 (/HDA) Q02457 (/HDA) Q02457 (/HDA) Q02457 (/HDA) Q02457 (/HDA) Q02457 (/HDA) Q6E434 (/HDA) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | Q6E434 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q6E434 (/IDA) |