The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 837: Histone acetyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
1 P34218 (/IDA)
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
1 P34218 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P34218 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin silencing GO:0006342
Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
1 A0A1D8PS09 (/NAS)
Chromatin silencing at telomere GO:0006348
Repression of transcription of telomeric DNA by altering the structure of chromatin.
1 P34218 (/IMP)
Covalent chromatin modification GO:0016569
The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.
1 P34218 (/IMP)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
1 P34218 (/IDA)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
1 P34218 (/IMP)
Chromatin silencing at silent mating-type cassette GO:0030466
Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.
1 P34218 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NuA3 histone acetyltransferase complex GO:0033100
A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p.
1 P34218 (/IDA)
NuA3a histone acetyltransferase complex GO:1990467
A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p.
1 P34218 (/IDA)
NuA3b histone acetyltransferase complex GO:1990468
A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.
1 P34218 (/IDA)