The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 731: Phenazine-specific methyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phenazine-1-carboxylate N-methyltransferase. [EC: 2.1.1.327]
S-adenosyl-L-methionine + phenazine-1-carboxylate = S-adenosyl-L- homocysteine + 5-methylphenazine-1-carboxylate.
  • The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism.
  • The enzyme is active in vitro only in the presence of EC 1.14.13.218.
169 A0A0F6U950 A0A0F6U950 A0A0F6U950 A0A0F6U950 A0A0F6U950 A0A0F6U950 A0A0F6U950 A0A0F6U950 A0A0F6U950 A0A0F6U950
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