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CATH Superfamily 1.10.10.10

Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 373: ArsR family transcriptional regulator

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
 13 P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA)
(3 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
 13 P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP)
(3 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 13 P9WMI9 (/IPI) P9WMI9 (/IPI) P9WMI9 (/IPI) P9WMI9 (/IPI) P9WMI9 (/IPI) P9WMI9 (/IPI) P9WMI9 (/IPI) P9WMI9 (/IPI) P9WMI9 (/IPI) P9WMI9 (/IPI)
(3 more)
Lead ion binding GO:0032791
Interacting selectively and non-covalently with lead (Pb) ions.
 13 P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA)
(3 more)
Cadmium ion binding GO:0046870
Interacting selectively and non-covalently with cadmium (Cd) ions.
 13 P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA)
(3 more)
Cadmium ion sensor activity GO:0097063
Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++).
 13 P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA)
(3 more)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to lead ion GO:0010288
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
 13 P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP)
(3 more)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
 13 P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA) P9WMI9 (/IDA)
(3 more)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
 13 P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP) P9WMI9 (/IMP)
(3 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.