CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 15: Leucine-responsive transcriptional regulator Lrp
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
189 |
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
(179 more) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
185 |
O05140 (/IPI)
O05140 (/IPI)
O05140 (/IPI)
O05140 (/IPI)
O05140 (/IPI)
O05140 (/IPI)
O05140 (/IPI)
O05140 (/IPI)
O05140 (/IPI)
O05140 (/IPI)
(175 more) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
178 |
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
(168 more) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
178 |
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
(168 more) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
174 |
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
(164 more) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
174 |
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
(164 more) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
174 |
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
(164 more) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
174 |
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
(164 more) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
174 |
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
(164 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
174 |
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
P0ACJ0 (/IPI)
(164 more) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
174 |
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
P0ACJ0 (/IDA)
(164 more) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
15 |
Q7MLV6 (/IDA)
Q7MLV6 (/IDA)
Q7MLV6 (/IDA)
Q7MLV6 (/IDA)
Q9KQU4 (/IDA)
Q9KQU4 (/IDA)
Q9KQU4 (/IDA)
Q9KQU4 (/IDA)
Q9KQU4 (/IDA)
Q9KQU4 (/IDA)
(5 more) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
11 |
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
(1 more) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
174 |
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
(164 more) |
|
Leucine biosynthetic process GO:0009098
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
|
174 |
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
(164 more) |
|
Response to leucine GO:0043201
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.
|
174 |
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
P0ACJ0 (/IMP)
(164 more) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
174 |
P0ACJ0 (/IEP)
P0ACJ0 (/IEP)
P0ACJ0 (/IEP)
P0ACJ0 (/IEP)
P0ACJ0 (/IEP)
P0ACJ0 (/IEP)
P0ACJ0 (/IEP)
P0ACJ0 (/IEP)
P0ACJ0 (/IEP)
P0ACJ0 (/IEP)
(164 more) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
11 |
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
(1 more) |
|
Leucine metabolic process GO:0006551
The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.
|
11 |
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
(1 more) |
|
Leucine transport GO:0015820
The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
11 |
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
Q9KQU4 (/ISS)
(1 more) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.