The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1097: Helix-turn-helix transcriptional regulator

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
6 Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
6 Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
6 Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
6 Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
6 Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP)
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
6 Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of multi-organism process GO:0043902
Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
6 Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP)
Positive regulation of secondary metabolite biosynthetic process GO:1900378
Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.
6 Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
6 Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA) Q9I0P6 (/IDA)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
6 Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP) Q9I0P6 (/IMP)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
6 Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI) Q9I0P6 (/IPI)