CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family serine/threonine-protein kinase unc-51 isoform X1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O75385
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O75385
ULK1_HUMAN
Homo sapiens
Serine/threonine-protein kinase ULK1

PDB Structure

PDB 6QAS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2).
Chaikuad, A., Koschade, S.E., Stolz, A., Zivkovic, K., Pohl, C., Shaid, S., Ren, H., Lambert, L.J., Cosford, N.D.P., Brandts, C.H., Knapp, S.
Biochem.J.