CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.630 | Aminopeptidase | |
3.40.630.10 | Zn peptidases |
Domain Context
CATH Clusters
Superfamily | Zn peptidases |
Functional Family | Carboxypeptidase A1 |
Enzyme Information
3.4.17.1 |
Carboxypeptidase A.
based on mapping to UniProt P15085
Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.
-!- Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells and skeletal muscle. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.
|
UniProtKB Entries (1)
P15085 |
CBPA1_HUMAN
Homo sapiens
Carboxypeptidase A1
|
PDB Structure
PDB | 6I6Z |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes.
J. Med. Chem.
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