CATH Classification

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Lysine-specific demethylase 4A

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt O75164

UniProtKB Entries (1)

P10412
H14_HUMAN
Homo sapiens
Histone H1.4

PDB Structure

PDB 6H8P
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mechanistic and structural studies of KDM-catalysed demethylation of histone 1 isotype 4 at lysine 26.
Walport, L.J., Hopkinson, R.J., Chowdhury, R., Zhang, Y., Bonnici, J., Schiller, R., Kawamura, A., Schofield, C.J.
FEBS Lett.