CATH Domain 6fqqE01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.60	Homeodomain-like

Domain Context

CATH Clusters

Superfamily	Homeodomain-like
Functional Family	TGFB-induced factor homeobox 1

Enzyme Information

UniProtKB Entries (1)

TGIF1_HUMAN

Homo sapiens

Homeobox protein TGIF1

PDB Structure

PDB	6FQQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-beta signaling. Guca, E., Sunol, D., Ruiz, L., Konkol, A., Cordero, J., Torner, C., Aragon, E., Martin-Malpartida, P., Riera, A., Macias, M.J. Nucleic Acids Res.