1 keywords

CATH Domain 6erfD02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.290 Ku70; Chain: A; Domain 2
Homologous Superfamily 2.40.290.10  

Domain Context

CATH Clusters

Superfamily 2.40.290.10
Functional Family X-ray repair cross-complementing protein 5

Enzyme Information

3.6.4.-
Acting on ATP; involved in cellular and subcellular movement.
based on mapping to UniProt P13010

UniProtKB Entries (1)

P13010
XRCC5_HUMAN
Homo sapiens
X-ray repair cross-complementing protein 5

PDB Structure

PDB 6ERF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nemoz, C., Ropars, V., Frit, P., Gontier, A., Drevet, P., Yu, J., Guerois, R., Pitois, A., Comte, A., Delteil, C., Barboule, N., Legrand, P., Baconnais, S., Yin, Y., Tadi, S., Barbet-Massin, E., Berger, I., Le Cam, E., Modesti, M., Rothenberg, E., Calsou, P., Charbonnier, J.B.
Nat. Struct. Mol. Biol.