CATH Domain 6cp6F03
|1.10.1140||Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3|
|1.10.1140.10||Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3|
|Superfamily||Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3|
|Functional Family||ATP synthase subunit beta|
H(+)-transporting two-sector ATPase.
based on mapping to UniProt P00830
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2).
-!- A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. -!- Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (F(o), V(o), A(o)) and a cytoplasmic-compartment sector (F(1), V(1), A(1)). -!- The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases. -!- All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits. -!- Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. -!- This movement is driven by the H(+) electrochemical potential gradient. -!- The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP. -!- Formerly EC 188.8.131.52 and EC 184.108.40.206.
UniProtKB Entries (1)
Saccharomyces cerevisiae S288C
ATP synthase subunit 5, mitochondrial
High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane.