CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.472 | Cyclin A; domain 1 |
|
1.10.472.10 | Cyclin-like |
Domain Context
CATH Clusters
| Superfamily | Cyclin-like |
| Functional Family | Cyclin-K (Predicted) |
Enzyme Information
UniProtKB Entries (1)
| Q9NYV4 |
CDK12_HUMAN
Homo sapiens
Cyclin-dependent kinase 12
|
PDB Structure
| PDB | 6CKX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors.
J. Med. Chem.
|