CATH Classification

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q5RZ08
Q5RZ08_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 6CDJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis.
Ghosh, A.K., R Nyalapatla, P., Kovela, S., Rao, K.V., Brindisi, M., Osswald, H.L., Amano, M., Aoki, M., Agniswamy, J., Wang, Y.F., Weber, I.T., Mitsuya, H.
J. Med. Chem.