CATH Classification

Domain Context

CATH Clusters

Superfamily Leucine Dehydrogenase, chain A, domain 1
Functional Family Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic

Enzyme Information

4.2.1.10
3-dehydroquinate dehydratase.
based on mapping to UniProt Q9SQT8
3-dehydroquinate = 3-dehydroshikimate + H(2)O.
1.1.1.25
Shikimate dehydrogenase.
based on mapping to UniProt Q9SQT8
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

Q9SQT8
DHQSD_ARATH
Arabidopsis thaliana
Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic

PDB Structure

PDB 6BMQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and biochemical approaches uncover multiple evolutionary trajectories of plant quinate dehydrogenases.
Gritsunov, A., Peek, J., Diaz Caballero, J., Guttman, D., Christendat, D.
Plant J.