CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.1270 | Trp Operon Repressor; Chain A | |
1.10.1270.20 | tRNA(m1g37)methyltransferase, domain 2 |
Domain Context
CATH Clusters
Superfamily | tRNA(m1g37)methyltransferase, domain 2 |
Functional Family | tRNA (guanine-N(1)-)-methyltransferase |
Enzyme Information
UniProtKB Entries (0)
PDB Structure
PDB | 5ZHN |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
J.Med.Chem.
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