CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome c oxidase-like, subunit I domain
Functional Family Cytochrome c oxidase subunit 1

Enzyme Information

1.9.3.1
Cytochrome-c oxidase.
based on mapping to UniProt P00396
4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.
-!- The reduction of O(2) to water is accompanied by the extrusion of four protons from the intramitochondrial compartment. -!- Several bacteria appear to contain analogous oxidases.

UniProtKB Entries (1)

P04038
COX6C_BOVIN
Bos taurus
Cytochrome c oxidase subunit 6C

PDB Structure

PDB 5ZCQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray structural analyses of azide-bound cytochromecoxidases reveal that the H-pathway is critically important for the proton-pumping activity.
Shimada, A., Hatano, K., Tadehara, H., Yano, N., Shinzawa-Itoh, K., Yamashita, E., Muramoto, K., Tsukihara, T., Yoshikawa, S.
J. Biol. Chem.