CATH Classification

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family Putative cyclin-c

Enzyme Information

UniProtKB Entries (1)

P49336
CDK8_HUMAN
Homo sapiens
Cyclin-dependent kinase 8

PDB Structure

PDB 5XS2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of potent and selective CDK8 inhibitors through FBDD approach
Han, X., Jiang, M., Zhou, C., Zhou, Z., Xu, Z., Wang, L., Mayweg, A.V., Niu, R., Jin, T.G., Yang, S.
Bioorg. Med. Chem. Lett.